Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan (2024)

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Volume 13

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10.3390/jcm13102967

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Article

by

Atsushi f*ckunaga

Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan (5)Atsushi f*ckunaga

Atsushi f*ckunaga is an Associate Professor, Department of Dermatology, Division of Medicine for and[...]

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1Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan (6),

Yuko Kishi

2,*,

Kazuhiko Arima

Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan (8)Kazuhiko Arima

2Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan (9) and

Hiroyuki Fujita

Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan (10)Hiroyuki Fujita

2

1

Department of Dermatology, Division of Medicine for Function and Morphology of Sensory Organs, Faculty of Medicine, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan

2

Specialty Care Medical, Sanofi K.K., Tokyo Opera City Tower, 3-20-2, Nishi Shinjuku, Tokyo 163-1488, Japan

*

Author to whom correspondence should be addressed.

J. Clin. Med. 2024, 13(10), 2967; https://doi.org/10.3390/jcm13102967

Submission received: 26 March 2024/Revised: 15 May 2024/Accepted: 16 May 2024/Published: 17 May 2024

(This article belongs to the Special Issue Chronic Inflammatory Skin Diseases: An Update for Clinician—Part II)

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Abstract

Background: Chronic spontaneous urticaria (CSU), characterized by the recurrence of pruritic hives and/or angioedema for >6 weeks with no identifiable trigger, has a negative impact on health-related quality of life (HRQoL). Methods: The objective of this web-based cross-sectional study was to evaluate disease control, disease burden, and treatment satisfaction in Japanese adults with CSU using the Urticaria Control Test (UCT), HRQoL outcomes, and the Treatment Satisfaction Questionnaire for Medication–9 items (TSQM-9). Results: In total, 529 adults were included in the analysis (59.9% female), with a mean ± standard deviation (SD) in CSU duration of 13.2 ± 13.0 years. Based on UCT scores, two-thirds of patients had poor (score of 0–7; 23.6%) or insufficient (score of 8–11; 43.3%) symptom control, and one-third had good control (score of 12–16; 33.1%). Overall treatment satisfaction was not high, with mean ± SD TSQM-9 scores of 55.5 ± 17.6% for effectiveness, 68.2 ± 18.8% for convenience, and 59.2 ± 18.4% for global satisfaction. No apparent differences in TSQM-9 scores were observed between patients receiving different medications. HRQoL outcomes were worse among patients with poor/insufficient symptom control. Conclusions: Japanese adults with CSU have a high disease burden, and better treatment options are needed to increase treatment satisfaction.

Keywords: chronic spontaneous urticaria; chronic urticaria; Japan; patient reported outcome measures; patient satisfaction

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MDPI and ACS Style

f*ckunaga, A.; Kishi, Y.; Arima, K.; Fujita, H.Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan. J. Clin. Med. 2024, 13, 2967.https://doi.org/10.3390/jcm13102967

AMA Style

f*ckunaga A, Kishi Y, Arima K, Fujita H.Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan. Journal of Clinical Medicine. 2024; 13(10):2967.https://doi.org/10.3390/jcm13102967

Chicago/Turabian Style

f*ckunaga, Atsushi, Yuko Kishi, Kazuhiko Arima, and Hiroyuki Fujita.2024. "Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan" Journal of Clinical Medicine 13, no. 10: 2967.https://doi.org/10.3390/jcm13102967

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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MDPI and ACS Style

f*ckunaga, A.; Kishi, Y.; Arima, K.; Fujita, H.Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan. J. Clin. Med. 2024, 13, 2967.https://doi.org/10.3390/jcm13102967

AMA Style

f*ckunaga A, Kishi Y, Arima K, Fujita H.Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan. Journal of Clinical Medicine. 2024; 13(10):2967.https://doi.org/10.3390/jcm13102967

Chicago/Turabian Style

f*ckunaga, Atsushi, Yuko Kishi, Kazuhiko Arima, and Hiroyuki Fujita.2024. "Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan" Journal of Clinical Medicine 13, no. 10: 2967.https://doi.org/10.3390/jcm13102967

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan (11)

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Disease Control and Treatment Satisfaction in Patients with Chronic Spontaneous Urticaria in Japan (2024)

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